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Antioxidants: The Neutral Scientific Truth, Evidence-Based Benefits of Health, and Important Reality

General Health

Antioxidants: The Neutral Scientific Truth, Evidence-Based Benefits of Health, and Important Reality

Antioxidants: The Neutral Scientific Truth, Evidence-Based Benefits of Health, and Important Reality

In This Article
  • Overview
  • Free Radicals
  • Antioxidants
  • Health Benefits
  • Nutritional Sources
  • Supplements
  • Risks
  • Conclusion


What is an Antioxidant and why is it Important?

Antioxidants are a basic portion of optimum wellness, along with the spotlight is slowly increasing on those critical nutrients. The usage of the phrase’antioxidants’ has become rather common in tagging certain products or foods to market their health advantages.

But, few individuals actually understand what they are or how they operate in the human body.

This report dives to exactly what antioxidants have been, their purpose, their possible health benefits, sources of fats, and also some other dangers involved with supplements.

Free Radicals and the Role of Antioxidants


Free radicals

To be able to comprehend the function of antioxidants within your system, it’s crucial that you understand the function of free radicals and oxidative stress. Electrons usually exist in pairs and also if that free radical adventures a different molecule, it can throw an electron out of it to match with its odd electron.

The next molecule, with missing an electron, itself becomes a free radical. This produces a chain reaction of free radical production, also called oxidation. “Oxidative stress” is a consequence of this lengthy chain response. This manufacturing and accumulation of free radicals may cause cell damage, such as damage to DNA, proteins, lipids, and other cells. Free radicals and oxidative stress have been considered to play an important part in preventing aging and an assortment of ailments, such as cancer, cardiovascular disorders, diabetes, and Alzheimer’s disease, Parkinson’s disease, along with eye disorders such as cataracts and adrenal disorders degeneration.

Free radicals can be observed in almost all harmful substances, such as air pollutants, cigarette smoke, and other toxins, and so are created whenever the human body is subjected to radiation, for example, sunlight.

They’re also generated when the body burns food to get energy and breaks down harmful compounds in the liver, or even combats diseases.

Your own body’s white blood cells create large amounts of free radicals to destroy germs and virus-infected cells. Free radicals operate as communication compounds that encourage or preserve inflammatory reactions, and also in chronic inflammation, normal healthful cells can get damaged.

Other lifestyle, stress, and environmental factors are known to promote the excessive free radical formation and oxidative stress include:

  • Excessive intake of antioxidants, such as vitamins C and E
  • Too much or too little oxygen in the body
  • Alcohol intake
  • High intake of polyunsaturated fatty acids
  • Excessive intake of iron, magnesium, copper, or zinc
  • High blood sugar levels
  • Intense and prolonged exercise, causing tissue damage
  • Antioxidant deficiency


The definition of fats has been”any substance that inhibits oxidation, particularly one employed to counteract the deterioration of preserved food items or eliminate potentially harmful oxidizing agents at a living organism”.

Antioxidants are natural or man-made chemicals that may stop or delay some sorts of cell damage. Antioxidants may also fix and/or clean cells that are damaged, and a few antioxidants may cause biosynthesis of different antioxidants or shield enzymes too.

Antioxidants are crucial for the survival of living things, such as animals and plants. The body creates many distinct antioxidants (also referred to as polyunsaturated fats ) to guard itself from various ailments because of tissue injury.

Your body is not able to create some crucial antioxidants and consequently, external resources, such as meals or nutritional supplements, are crucial in providing these fats. These naturally-occurring antioxidants can also be known as polyunsaturated fats.

Antioxidants may be broken down into two groups, polyunsaturated fats, along with non-enzymatic antioxidants. Enzymatic antioxidants are forms of antioxidant enzymes that interact and protect tissues from oxidative stress.

Antioxidants that are produced in the body include, but are not limited to:

  • Catalase (enzymatic)
  • Superoxide dismutase (SOD) (enzymatic)
  • Metal-binding proteins (examples – transferrin and albumin)
  • Alpha-lipoic acid
  • Glutathione and the whole glutathione system (enzymatic)
  • Ubiquinol (Coenzyme Q10)
  • Uric acid
  • Melatonin
  • Bilirubin

Examples of antioxidants that are essential from food include, but are not limited to:

  • Vitamin E (tocopherols and tocotrienols)
  • Carotenoids (especially beta-carotene, zeaxanthin, lycopene, and lutein)
  • Vitamin C (ascorbic acid)
  • Resveratrol
  • L-arginine
  • Flavonoids (including rutin and quercetin)
  • Anthocyanins (a type of flavonoid polyphenol phytonutrient)
  • Selenium
  • Omega-3 fatty acids
  • Manganese
  • Glutathione


The Health Benefits of Antioxidants

Recent research has shown that the antioxidants of plant sources with anti-inflammatory scavenging properties may have great importance as therapeutic agents in several diseases brought on by oxidative stress.

Research suggests that when it comes to longevity and overall health, some of the benefits of consuming antioxidant foods, herbs, teas, and supplements include:

  • Healthier, more youthful, glowing skin
  • Reduced cancer risk
  • Reduced risks for vision loss or disorders, like macular degeneration and cataracts
  • Slower signs of aging, including the skin, eyes, tissue, joints, heart, and brain
  • Longer life span
  • Reduced risk for other chronic diseases
  • Detoxification support
  • Less risk for cognitive problems, such as dementia
  • Protection against heart disease and stroke

Antioxidants are also often employed as food additives since they may improve the shelf life of the organic and processed foods, because of their function of decreasing oxidation.

Antioxidants from Nutrition Sources

Studies have shown that nutrition plays an essential part in preventing chronic diseases, since most of them may be associated with diet.

Functional food expands the notion of believing food not just essential for dwelling but also as an outcome of psychological and bodily well-being, leading to the avoidance and reduction of risk factors for many ailments or improving certain physiological purposes. Normal ingestion of vegetables and fruits continues to be known as lowering the possibility of chronic ailments and research reveals an underactive diet has a rather positive health effect in the long term. These include vegetables, fruits, whole grains, seeds, nuts, spices and herbs, and sometimes even cocoa. Wild-caught fatty fish and grass-fed/wild beef, and eggs can also be sources of fats.

Nobody food group ought to be your only focus. Rather, make certain to include a number of fruits, veggies, nuts, whole grains, spices and herbs in your diet plan. Attempting to consume the colors of the rainbow will be able to help you get many different antioxidant nutrients and chemicals.

Listed below are some of the richest sources of antioxidants:

  • Alliums and other bulbs: garlic, onions, shallots, fennel bulbs, leeks, and scallions.
  • Vegetables: sweet potatoes, squash, carrots, red and green peppers, kale, lettuce, spinach, cucumber, green beans, mustard greens, broccoli, cauliflower, cabbage, Brussels sprouts, artichokes (boiled), mushrooms, eggplant, tomato, chili pepper, and kidney beans.
    • Try to choose red, orange, deep yellow and dark green leafy vegetables every day!
  • Other sources of healthy fats: extra-virgin olive oil, macadamia oil, avocado oil, coconut oil, and olives.
  • Whole-grains: wheat germ, maize, whole wheat, barley, rye, quinoa, etc.
  • Nuts and seeds: flax seeds, hemp seeds, chia seeds, sunflower seeds, pumpkin seeds, walnuts, pecans, and hazelnuts.
  • Spices: clove, cinnamon, oregano, turmeric, cumin, parsley, basil, curry powder, mustard seed, ginger, pepper, chili powder, paprika, garlic, coriander, onion, cardamom, nutmeg, caraway, and cayenne.
  • Wild-caught fatty fish: salmon, sardines, halibut, herring, mackerel, pollock, trout, tuna, and anchovies.
  • Herbs: sage, thyme, marjoram, tarragon, peppermint, rosemary, savory, basil, lemon balm, parsley, and dill weed.
  • Beverages: pomegranate juice, red wine, coffee, green tea, black tea, and white tea.
  • Dark chocolate/cocoa: at least 70% dark chocolate.

Antioxidants from Supplements

Most clinical trials of antioxidant supplements haven’t discovered them to present significant health benefits. Researchers have proposed many reasons for it, including the following:

  • The beneficial health effects of a diet high in fruits and veggies or alternative antioxidant-rich foods could possibly be brought on by other compounds within exactly the very same foods, other nutritional factors, along with other lifestyle options instead of antioxidants.

  • Differences in the chemical makeup of carbohydrates in foods versus individuals in nutritional supplements can affect their consequences.
    For a number of diseases, certain antioxidants may be more powerful than those which were analyzed. By way of instance, to reduce eye ailments, antioxidants that exist in the eye, like lutein, could be more advantageous than individuals not located at heart, for example beta-carotene.

  • Important to note that there have been some studies showing benefits to antioxidant supplements, including the Age-Related Eye Disease Study (AREDS), which showed that a combination of antioxidants (vitamin C, vitamin E, and beta-carotene) and zinc reduced the risk of developing the advanced stage of age-related macular degeneration by 25% in people who had the intermediate stage of this disease or who had the advanced stage in only one eye.

It’s very important to be aware that there are several studies demonstrating benefits to antioxidant nutritional supplements, for instance, Age-Related Eye Disease Study (AREDS), that revealed that a mix of antioxidants (vitamin C, vitamin E, vitamin along with beta-carotene) and magnesium decreased the chance of creating the advanced phase of esophageal macular degeneration by 25 percent in people who’d the intermediate phase of the disorder or that had the complex phase in just 1 eye.

AREDS2a followup research discovered that incorporating lutein and zeaxanthin enhanced the nutritional supplement’s efficacy in people who weren’t carrying beta-carotene and individuals who consumed only tiny quantities of lutein and zeaxanthin in meals. Quercetin may also be safe and beneficial for helping handle several inflammatory health issues.


Risks to Antioxidant Supplements

Excessive ingestion of polyunsaturated fats may have toxic effects and might even promote cognitive damage, as opposed to stop it. This occurrence is referred to as the”anti-oxidant”.

By way of instance, the consequences of several studies have linked using high-dose beta-carotene nutritional supplements into an increased chance of lung cancer from smokers. It’s likewise very important to use care if you’re nursing or pregnant or contemplating giving a kid a nutritional supplement. Be certain that you consult your healthcare provider ahead.

Like other nutritional supplements, antioxidant nutritional supplements may interact with certain medicines, such as:
Vitamin E supplements might increase the chance of bleeding in people that are taking antipsychotic drugs (“blood thinners”).
If you’re in danger of cardiovascular disease or some other chronic ailments or possess celiac disease degeneration, seek advice from your wellbeing care providers to ascertain if or not a nutritional supplement may help you.


Antioxidants are a basic portion of optimum wellbeing. The body creates specific antioxidants, though other antioxidants have to be provided from sources beyond the body.

It is obviously perfect, and generally more valuable, to get fats or other nutritional supplements straight from actual food resources, especially plant-based food resources.

But, certain kinds could be useful when consumed supplement form, however, it’s necessary to consult your physician beforehand.

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